SCHEMBL28043207

SCHEMBL28043207

CC(C)c1ccc(Cc2ccc(O)cc2)c(C(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.44
ESR2 Q92731 4/20 0.44
TAAR1 Q96RJ0 3/20 0.42
SLC6A2 P23975 1/20 0.42
KEAP1 Q14145 1/20 0.41
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
ALOX5 P09917 2/20 0.39
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
TRPA1 O75762 1/20 0.38
PTGS1 P23219 1/20 0.38
CACNA1C Q13936 1/20 0.38
TYR P14679 1/20 0.38
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
ALOX12 P18054 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27383713 0.87 ESR1 (0.44) ESR1ESR2TAAR1SLC6A2KEAP1
SCHEMBL27628516 0.83 IDO1 (0.33) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL5050256 0.82 FABP3 (0.41) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL27648531 0.80 FABP3 (0.33) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL31545899 0.78 MEN1 (0.67) ESR1ESR2KEAP1MEN1MAPT
SCHEMBL5762395 0.78 ESR1 (0.64) ESR1ESR2TAAR1SLC6A2MAPT
SCHEMBL27906811 0.77 TYR (0.39) TYRALDH1A1
SCHEMBL22965747 0.75 MEN1 (0.50) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL28043208 0.75 HSPA5 (0.52) SLC6A2KEAP1MAPTGABRA1GABRB2
SCHEMBL9686320 0.74 ACE2 (0.42) SLC6A2GABRA1GABRB2TRPA1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105237359-A Preparation method of phenethyl/cumenyl phenol chemicals UNIV LIAONING 2016-01-13 CN disclosed