Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16008532 | 0.90 | BRD4 (1.00) | BRD4PIM1PIM2 | |
| SCHEMBL16008119 | 0.78 | BRD4 (0.77) | BRD4 | |
| SCHEMBL16008197 | 0.75 | BRD4 (0.71) | BRD4MAPT | |
| SCHEMBL16008879 | 0.74 | BRD4 (1.00) | BRD4 | |
| SCHEMBL16008205 | 0.74 | BRD4 (0.69) | BRD4 | |
| SCHEMBL16008102 | 0.73 | BRD4 (0.59) | BRD4MAPT | |
| SCHEMBL16008817 | 0.70 | BRD4 (0.64) | BRD4 | |
| SCHEMBL16007488 | 0.70 | BRD4 (1.00) | BRD4 | |
| SCHEMBL16008919 | 0.67 | BRD4 (0.59) | BRD4MAPT | |
| SCHEMBL16007949 | 0.66 | BRD4 (1.00) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164127-A | Bromodomain inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | claimed |
| CN-105164127-A | Bromodomain inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |