Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 15/20 | 0.77 |
| ▸ | EGFR | P00533 | 4/20 | 0.61 |
| ▸ | BTK | Q06187 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15938434 | 0.88 | MAPK3 (0.84) | MAPK3MAPK1 | |
| SCHEMBL15938583 | 0.87 | MAPK3 (1.00) | MAPK3EGFRBTK | |
| SCHEMBL15948403 | 0.80 | MAPK3 (1.00) | MAPK3MAPK1 | |
| SCHEMBL15938263 | 0.80 | MAPK3 (0.85) | MAPK3EGFRBTK | |
| SCHEMBL17616305 | 0.79 | MAPK3 (0.72) | MAPK3EGFRBTKMAPK1 | |
| SCHEMBL18857569 | 0.78 | MAPK3 (0.68) | MAPK3MAPK1 | |
| SCHEMBL15938288 | 0.78 | MAPK3 (0.83) | MAPK3MAPK1 | |
| SCHEMBL15938671 | 0.78 | MAPK3 (1.00) | MAPK3MAPK1 | |
| SCHEMBL17533927 | 0.77 | MAPK3 (0.83) | MAPK3MAPK1 | |
| SCHEMBL18857581 | 0.77 | MAPK3 (0.81) | MAPK3EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188371-A | Erk inhibitors and uses thereof | CELGENE AVILOMICS RES INC | 2015-12-23 | — | — | CN | disclosed |