Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26626453 | 0.84 | HRH3 (0.48) | EPHX1HRH3HRH4NPC1HPGD | |
| SCHEMBL288502 | 0.84 | HRH3 (0.48) | EPHX1HRH3HRH4NPC1HPGD | |
| SCHEMBL283254 | 0.84 | HRH3 (0.48) | EPHX1HRH3HRH4NPC1HPGD | |
| SCHEMBL11533140 | 0.81 | HRH3 (0.45) | EPHX1HRH3HRH4NPC1HPGD | |
| SCHEMBL28044008 | 0.81 | HRH3 (0.45) | HRH3HRH4NPC1HPGDRAB9A | |
| SCHEMBL21359154 | 0.80 | HRH3 (0.49) | EPHX1HRH3HRH4NPC1HPGD | |
| SCHEMBL15757827 | 0.78 | HRH3 (0.48) | EPHX1HRH3HRH4NPC1HPGD | |
| SCHEMBL29368166 | 0.77 | HRH3 (0.56) | HRH3HRH4ACHE | |
| SCHEMBL15589935 | 0.77 | EPHX1 (0.47) | EPHX1HRH3HRH4NPC1HPGD | |
| SCHEMBL6988966 | 0.77 | EPHX1 (0.47) | EPHX1HRH3HRH4NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189453-A | Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b | JANSSEN R & D IRELAND | 2015-12-23 | — | — | CN | disclosed |