Trolamine

Trolamine

SCHEMBL28044314

CN(C)CCN(C)C.OCCN(CCO)CCO

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.69
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
ALDH1A1 P00352 4/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HPGD P15428 2/20 0.36
MAPK1 P28482 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13187870 0.97 MAPT (0.65) MAPTCA12CA2CA3CA4
SCHEMBL332813 0.97 MAPT (0.65) MAPTCA12CA2CA3CA4
SCHEMBL5891988 0.97 MAPT (0.65) MAPTCA12CA2CA3CA4
Hydrochloric Acid SCHEMBL27157431 0.94 MAPT (0.61) MAPTCA12CA2CA3CA4
Trolamine SCHEMBL15410677 0.93 MAPT (0.80) MAPTCA12CA2CA3CA4
SCHEMBL23117067 0.87 MAPT (0.52) MAPTCA12CA2CA3CA4
Trolamine SCHEMBL8980487 0.87 MAPT (0.52) MAPTCA12CA2CA3CA4
SCHEMBL9715505 0.87 MAPT (0.52) MAPTCA12CA2CA3CA4
Trolamine SCHEMBL5918852 0.86 MAPT (0.56) MAPTCA12CA2CA9ALDH1A1
SCHEMBL571030 0.85 MAPT (0.58) MAPTCA12CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105120910-B Method for material to be formed in situ in medical instrument 恩朵罗杰克斯股份有限公司 2019-04-12 CN disclosed
CN-105120910-A Method for forming materials in situ within a medical device ENDOLOGIX INC 2015-12-02 CN disclosed