Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.56 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.56 |
| ▸ | FLT3 | P36888 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480036 | 0.89 | FLT3 (0.47) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL6478966 | 0.87 | SMN1; SMN2 (0.51) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL24138422 | 0.87 | PIM1 (0.51) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL8716521 | 0.86 | PRMT1 (0.59) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL7410565 | 0.85 | PIM1 (0.66) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| Hydrochloric Acid SCHEMBL8713031 | 0.84 | PRMT1 (0.58) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL28125380 | 0.83 | KDM4E (0.46) | FLT3NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6480210 | 0.83 | PSMB8 (0.51) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL6407371 | 0.81 | FLT3 (0.76) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL1877753 | 0.80 | PIM1 (0.45) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130705-B | Benzo five-membered unsaturated heterocycle compound or its pharmaceutical salts and preparation method thereof, pharmaceutical composition and application thereof | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-04-20 | — | — | CN | disclosed |