Benzene

Benzene

SCHEMBL28044738

Cn1cnc(CO)c1.c1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 2/20 0.53
TSHR P16473 1/20 0.53
MTOR P42345 1/20 0.53
HRH4 Q9H3N8 1/20 0.53
HRH3 Q9Y5N1 1/20 0.53
TDP1 Q9NUW8 1/20 0.52
NOTUM Q6P988 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2E1 P05181 1/20 0.34
CYP2A6 P11509 1/20 0.34
CYP2B6 P20813 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.33
P2RX7 Q99572 1/20 0.32
LTA4H P09960 1/20 0.32
OGA O60502 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL743854 0.96
Hydrochloric Acid SCHEMBL1186779 0.93
SCHEMBL9597765 0.78
SCHEMBL27340963 0.75 CYP2C9 (0.50) CYP2C9CYP2C19TSHRMTORHRH4
SCHEMBL876467 0.75 CYP2C9 (0.50) CYP2C9CYP2C19TSHRMTORHRH4
SCHEMBL6132965 0.75 CYP2C9 (0.60) CYP2C9CYP2C19TSHRMTORHRH4
SCHEMBL419467 0.75
Hydrochloric Acid SCHEMBL1373085 0.74 TDP1 (0.52) CYP2C9CYP2C19TSHRMTORHRH4
SCHEMBL9602988 0.73
SCHEMBL246132 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105073820-A Thermosetting resin composition YOKOHAMA RUBBER CO LTD 2015-11-18 CN disclosed