Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Anhydride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TYMS | P04818 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Anhydride SCHEMBL28279463 | 0.92 | TDP1 (0.88) | TDP1ALOX15HSD17B10ALDH1A1KDM4E | |
| SCHEMBL19818355 | 0.89 | TDP1 (0.93) | TDP1ALOX15HSD17B10ALDH1A1KDM4E | |
| Phthalic Anhydride SCHEMBL5679433 | 0.89 | TDP1 (0.93) | TDP1ALOX15HSD17B10ALDH1A1KDM4E | |
| Phthalic Anhydride SCHEMBL6245052 | 0.87 | TDP1 (0.70) | TDP1ALOX15HSD17B10ALDH1A1KDM4E | |
| Phthalic Anhydride SCHEMBL220 | 0.86 | TDP1 (1.00) | TDP1ALOX15HSD17B10ALDH1A1KDM4E | |
| Phthalic Anhydride SCHEMBL380499 | 0.86 | TDP1 (1.00) | TDP1ALOX15HSD17B10ALDH1A1KDM4E | |
| Phthalic Anhydride SCHEMBL29356227 | 0.86 | TDP1 (1.00) | TDP1ALOX15HSD17B10ALDH1A1KDM4E | |
| Phthalic Anhydride SCHEMBL28312940 | 0.85 | TDP1 (0.67) | TDP1ALOX15HSD17B10ALDH1A1KDM4E | |
| Phthalic Anhydride SCHEMBL28312948 | 0.85 | TDP1 (0.67) | TDP1ALOX15HSD17B10ALDH1A1KDM4E | |
| Phthalic Anhydride SCHEMBL31125295 | 0.84 | TDP1 (0.58) | TDP1ALOX15HSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153987-A | Process for producing glue by adopting phthalic anhydride series polyatomic alcohol as raw material | SHAOXING ECONOMICAL DEV ZONE ZHONGZE ADHESIVE TAPE FACTORY | 2015-12-16 | — | — | CN | claimed |
| CN-105153987-A | Process for producing glue by adopting phthalic anhydride series polyatomic alcohol as raw material | SHAOXING ECONOMICAL DEV ZONE ZHONGZE ADHESIVE TAPE FACTORY | 2015-12-16 | — | — | CN | disclosed |
| CN-105153987-A | Process for producing glue by adopting phthalic anhydride series polyatomic alcohol as raw material | SHAOXING ECONOMICAL DEV ZONE ZHONGZE ADHESIVE TAPE FACTORY | 2015-12-16 | — | — | CN | disclosed |