Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572033 | 0.76 | PTPN1 (0.66) | PTPN1PTPN2SLC6A2SLC6A4 | |
| SCHEMBL2934384 | 0.74 | PTPN1 (0.72) | PTPN1PTPN2CA12CA1CA9 | |
| SCHEMBL17073984 | 0.71 | TDP1 (0.53) | PDE3BPDE3AP2RY12PDE2ADRD3 | |
| SCHEMBL22893515 | 0.70 | PTPN2 (0.78) | PTPN1PTPN2 | |
| SCHEMBL22893421 | 0.68 | PTPN2 (0.78) | PTPN1PTPN2 | |
| SCHEMBL24914283 | 0.67 | PTPN2 (0.69) | PTPN1PTPN2 | |
| SCHEMBL470915 | 0.66 | TDP1 (0.66) | DRD3HRH3 | |
| SCHEMBL22412641 | 0.66 | PTPN1 (0.69) | PTPN1PTPN2 | |
| SCHEMBL22893308 | 0.66 | PTPN2 (0.77) | PTPN1PTPN2 | |
| SCHEMBL23539417 | 0.66 | PTPN1 (0.80) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105193821-A | Diabetes mellitus resistant oral medicine composition | ZHU ZHONGLIANG | 2015-12-30 | — | — | CN | disclosed |
| CN-105193800-A | Diabetes mellitus resistant oral medicine composition | ZHU ZHONGLIANG | 2015-12-30 | — | — | CN | disclosed |
| CN-105193801-A | Diabetes mellitus resistant oral medicine composition | ZHU ZHONGLIANG | 2015-12-30 | — | — | CN | disclosed |