Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045102 | 0.82 | ESR2 (0.53) | CYP2C9ESR2PARP10F2HDAC8 | |
| SCHEMBL2257887 | 0.82 | ESR2 (0.62) | CYP2C9ESR2CYP3A4 | |
| SCHEMBL2762400 | 0.79 | CYP2C9 (0.69) | CYP2C9ESR2PARP10HDAC8HDAC6 | |
| SCHEMBL247920 | 0.78 | ESR2 (0.61) | CYP2C9ESR2PARP10F2HDAC8 | |
| Hydrochloric Acid SCHEMBL28200483 | 0.77 | CYP2C9 (0.67) | CYP2C9PARP10HDAC8HDAC6HDAC1 | |
| SCHEMBL17963141 | 0.76 | HDAC8 (0.61) | CYP2C9PARP10HDAC8HDAC6HDAC1 | |
| SCHEMBL3547925 | 0.75 | ESR2 (0.39) | ESR2KDM4EPOLBMAPTTSHR | |
| SCHEMBL3544910 | 0.75 | ESR2 (0.39) | ESR2KDM4EPOLBMAPTTSHR | |
| SCHEMBL3547927 | 0.75 | ESR2 (0.39) | ESR2KDM4EPOLBMAPTTSHR | |
| SCHEMBL3544911 | 0.75 | ESR2 (0.39) | ESR2KDM4EPOLBMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102659630-B | A kind of hydroxamic acid compound and its production and use | CHENGDU DIAO JIUHONG PHARMACEUTICAL FACTORY (CN) | 2016-01-06 | — | — | CN | disclosed |