Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CETP | P11597 | 2/20 | 0.59 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498923 | 0.83 | CETP (0.53) | MEN1KMT2ACETPSOAT1EP300 | |
| SCHEMBL9395051 | 0.82 | CETP (0.77) | MEN1KMT2ACETPSOAT1EP300 | |
| SCHEMBL5878480 | 0.82 | CETP (0.77) | MEN1KMT2ACETPSOAT1EP300 | |
| SCHEMBL7814839 | 0.82 | MEN1 (0.68) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL28833417 | 0.81 | MEN1 (0.77) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL10703263 | 0.80 | CETP (0.73) | MEN1KMT2ACETPSOAT1EP300 | |
| SCHEMBL78300 | 0.80 | CETP (0.73) | MEN1KMT2ACETPSOAT1EP300 | |
| SCHEMBL2008072 | 0.79 | MEN1 (1.00) | MEN1KMT2AMAPTLMNATDP1 | |
| SCHEMBL7824542 | 0.78 | MEN1 (0.72) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL15894577 | 0.78 | EP300 (0.62) | MEN1KMT2ACETPSOAT1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105308030-A | Alkyl, fluoroalkyl-1,4-benzodiazepinone compounds | BRISTOL MYERS SQUIBB CO | 2016-02-03 | — | — | CN | disclosed |