Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320453 | 0.84 | CA12 (0.42) | TSHRALDH1A1HTTMAPTCHRNB2 | |
| SCHEMBL12847444 | 0.84 | TSHR (0.46) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL16991087 | 0.81 | TSHR (0.42) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL2058303 | 0.80 | TSHR (0.46) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL2058439 | 0.76 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL6822515 | 0.75 | TSHR (0.67) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL11345491 | 0.75 | TSHR (0.67) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL16384311 | 0.75 | — | — | |
| SCHEMBL9685058 | 0.74 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL25781 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209403-A | Environmentally friendly permanent quaternaries of polyamines and their use as clay stabilizers and methods for making and using same | CLEARWATER INT LLC | 2015-12-30 | — | — | CN | disclosed |