Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14948651 | 0.79 | TPMT (0.33) | TPMTGPR35 | |
| SCHEMBL26611383 | 0.77 | NQO2 (0.47) | KDM4EKMT2AMAPTALDH1A1 | |
| SCHEMBL525211 | 0.76 | AKR1C3 (0.55) | KMT2AHTTAKR1C3ALDH1A1 | |
| SCHEMBL525210 | 0.76 | AKR1C3 (0.55) | KMT2AHTTAKR1C3ALDH1A1 | |
| SCHEMBL6670809 | 0.75 | TPMT (0.44) | TPMTKDM4ERXRARXRBKMT2A | |
| SCHEMBL6670819 | 0.75 | TPMT (0.44) | TPMTKDM4ERXRARXRBKMT2A | |
| SCHEMBL6670817 | 0.75 | TPMT (0.44) | TPMTKDM4ERXRARXRBKMT2A | |
| SCHEMBL23722448 | 0.74 | PADI4 (0.32) | MAPTALDH1A1 | |
| SCHEMBL6373525 | 0.74 | ERN1 (0.39) | KDM4EL3MBTL1KMT2AHTTGABBR2 | |
| SCHEMBL1580085 | 0.73 | EGFR (0.49) | KDM4EKMT2AAKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209444-A | Benzo-fused heterocyclic derivatives useful as agonists of GPR120 | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |