Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL27547223 | 0.85 | TSHR (0.65) | TSHRMAOBMAOACYP19A1CYP3A4 | |
| Aniline SCHEMBL78839 | 0.85 | TSHR (0.65) | TSHRMAOBMAOACYP19A1CYP3A4 | |
| Aniline SCHEMBL10532792 | 0.85 | TSHR (0.65) | TSHRMAOBMAOACYP19A1CYP3A4 | |
| Aniline SCHEMBL1984004 | 0.83 | — | — | |
| Aniline SCHEMBL11818606 | 0.83 | — | — | |
| Aniline SCHEMBL9755597 | 0.83 | TSHR (1.00) | TSHRMAOBMAOACYP19A1CYP3A4 | |
| Aniline SCHEMBL11803 | 0.83 | — | — | |
| SCHEMBL22096536 | 0.83 | TSHR (1.00) | TSHRMAOBMAOACYP19A1CYP3A4 | |
| SCHEMBL18517570 | 0.83 | TSHR (1.00) | TSHRMAOBMAOACYP19A1CYP3A4 | |
| Aniline SCHEMBL30876135 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272904-B | N- phenylamide compound and its application | 中国科学院广州生物医药与健康研究院 | 2019-04-09 | — | — | CN | disclosed |
| CN-105272904-A | N-phenylamide compound and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2016-01-27 | — | — | CN | disclosed |