Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465985 | 0.89 | MGAM (0.57) | MGAMALDH1A1HTTNPSR1HPGD | |
| SCHEMBL11152987 | 0.88 | MGAM (0.45) | MGAMKDM4CALDH1A1HTTNPSR1 | |
| SCHEMBL9353615 | 0.81 | MGAM (0.56) | MGAMALDH1A1HTTNPSR1HPGD | |
| Hydrochloric Acid SCHEMBL23112333 | 0.79 | MGAM (0.54) | MGAMALDH1A1HTTNPSR1HPGD | |
| SCHEMBL2200090 | 0.79 | MGAM (0.57) | MGAMALDH1A1HTTNPSR1HPGD | |
| SCHEMBL30251757 | 0.78 | MGAM (0.56) | MGAMALDH1A1HTTNPSR1HPGD | |
| SCHEMBL4221331 | 0.78 | MGAM (0.56) | MGAMALDH1A1HTTNPSR1HPGD | |
| SCHEMBL21241470 | 0.78 | MGAM (0.56) | MGAMALDH1A1HTTNPSR1HPGD | |
| SCHEMBL29933753 | 0.78 | MGAM (0.56) | MGAMALDH1A1HTTNPSR1HPGD | |
| SCHEMBL23359976 | 0.78 | MGAM (0.56) | MGAMALDH1A1HTTNPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198786-B | Amides compound of aryl substitution and preparation method thereof, the pharmaceutical composition comprising it and its application | 中国医学科学院医药生物技术研究所 | 2018-06-29 | — | — | CN | disclosed |
| CN-105198786-A | Aryl-substituted amide compound, preparing method thereof, medicine composition comprising same, and application thereof | INST MED BIOTECHNOLOGY CAMS | 2015-12-30 | — | — | CN | disclosed |