Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.67 |
| ▸ | CHUK | O15111 | 3/20 | 0.65 |
| ▸ | LIMK1 | P53667 | 14/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.56 |
| ▸ | IKBKB | O14920 | 2/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.46 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15664710 | 0.80 | KIT (1.00) | KITCHUKLIMK1ROCK2IKBKB | |
| SCHEMBL15516554 | 0.78 | KIT (0.83) | KITLIMK1ROCK2ROCK1 | |
| SCHEMBL20195296 | 0.78 | LIMK1 (0.69) | KITLIMK1ROCK2ROCK1LIMK2 | |
| SCHEMBL3126315 | 0.72 | LIMK1 (1.00) | LIMK1ROCK2ROCK1LIMK2 | |
| SCHEMBL20184562 | 0.70 | JAK3 (0.54) | KITCHUKLIMK1ROCK2IKBKB | |
| SCHEMBL3119541 | 0.69 | LIMK1 (1.00) | LIMK1ROCK2ROCK1LIMK2JAK2 | |
| SCHEMBL15032705 | 0.68 | JAK3 (0.76) | JAK2JAK3 | |
| SCHEMBL19616376 | 0.67 | LIMK1 (1.00) | KITLIMK1ROCK2ROCK1LIMK2 | |
| SCHEMBL20184701 | 0.66 | JAK2 (0.61) | KITLIMK1ROCK2ROCK1JAK2 | |
| SCHEMBL9967152 | 0.65 | AKT1 (0.46) | KITLIMK1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105311585-A | Traditional Chinese medicine composition for treating cirrhosis | LI CHAOBIN | 2016-02-10 | — | — | CN | disclosed |