SCHEMBL28046601

SCHEMBL28046601

COC(=O)C[C@H](NC(=O)c1ccc(Cl)s1)C(=O)Nc1ccc(N2CCOCC2=O)cc1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28046598 1.00 F10 (0.81) F10
SCHEMBL28046599 1.00 F10 (0.81) F10
SCHEMBL4029834 0.92 F10 (0.77) F10
SCHEMBL4029840 0.92 F10 (0.77) F10
SCHEMBL28825009 0.91 F10 (0.82) F10
SCHEMBL28825008 0.91 F10 (0.82) F10
SCHEMBL4030741 0.91 F10 (0.82) F10
SCHEMBL4027992 0.91 F10 (0.82) F10
SCHEMBL4029026 0.90 F10 (0.84) F10
SCHEMBL4029022 0.90 F10 (0.84) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105294669-A Tenth factor inhibitor and preparation method and application thereof SHANDONG KAISEN PHARMA CO LTD 2016-02-03 CN disclosed