SCHEMBL28046632

SCHEMBL28046632

O=C(NC(Cc1cnc[nH]1)C(=O)Nc1ccc(N2CCOCC2=O)cc1)c1ccc(Cl)s1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28274518 0.85 F10 (0.53) F10
SCHEMBL28046569 0.85 F10 (0.70) F10
SCHEMBL28046568 0.85 F10 (0.70) F10
SCHEMBL4035918 0.85 F10 (0.85) F10
SCHEMBL4028556 0.85 F10 (0.85) F10
SCHEMBL4027038 0.85 F10 (0.85) F10
SCHEMBL4029180 0.84 F10 (0.84) F10
SCHEMBL4029184 0.84 F10 (0.84) F10
SCHEMBL4026212 0.84 F10 (1.00) F10
SCHEMBL4026217 0.84 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105294669-A Tenth factor inhibitor and preparation method and application thereof SHANDONG KAISEN PHARMA CO LTD 2016-02-03 — — CN disclosed
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