Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046627 | 1.00 | F10 (0.56) | F10PTGS2CA12CA1CA2 | |
| SCHEMBL28046626 | 1.00 | F10 (0.56) | F10PTGS2CA12CA1CA2 | |
| SCHEMBL13755807 | 0.88 | F10 (0.65) | F10PTGS2 | |
| SCHEMBL23466730 | 0.84 | F10 (0.52) | F10PTGS2 | |
| SCHEMBL23466729 | 0.84 | F10 (0.52) | F10PTGS2 | |
| SCHEMBL28974541 | 0.84 | F10 (0.52) | F10PTGS2 | |
| SCHEMBL28974538 | 0.84 | F10 (0.52) | F10PTGS2 | |
| SCHEMBL4029840 | 0.81 | F10 (0.77) | F10 | |
| SCHEMBL4029834 | 0.81 | F10 (0.77) | F10 | |
| SCHEMBL28046585 | 0.81 | F10 (0.56) | F10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294669-A | Tenth factor inhibitor and preparation method and application thereof | SHANDONG KAISEN PHARMA CO LTD | 2016-02-03 | — | — | CN | disclosed |