SCHEMBL28046916

SCHEMBL28046916

CC[C](C)CC(C)(O)CC

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133677 0.74 TSHR (0.32) TSHRTDP1
SCHEMBL28281425 0.74
SCHEMBL1986410 0.73
SCHEMBL3903716 0.72
SCHEMBL5049917 0.72
SCHEMBL14644733 0.72
SCHEMBL23931 0.71
SCHEMBL638308 0.70 TDP1 (0.45) HMGCRCHRM1TBXA2RADRA1ATSHR
Tert-Butanol SCHEMBL11220086 0.68 TSHR (0.43) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL1614263 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085565-A Preparation method for hydroxypropyl (butyl) disiloxane UNIV SHANDONG 2015-11-25 CN disclosed