Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18241057 | 0.92 | CYP19A1 (0.45) | CYP19A1AKR1C3MAPTPOLBSMN1; SMN2 | |
| SCHEMBL29692421 | 0.92 | CYP19A1 (0.55) | CYP19A1AKR1C3MAPTPOLBSMN1; SMN2 | |
| SCHEMBL23001814 | 0.92 | CYP19A1 (0.47) | CYP19A1AKR1C3MAPTPOLBSMN1; SMN2 | |
| SCHEMBL29692354 | 0.92 | CYP19A1 (0.47) | CYP19A1AKR1C3MAPTPOLBSMN1; SMN2 | |
| SCHEMBL21296973 | 0.92 | CYP19A1 (0.55) | CYP19A1AKR1C3MAPTPOLBSMN1; SMN2 | |
| SCHEMBL22795533 | 0.92 | CYP19A1 (0.57) | CYP19A1AKR1C3MAPTPOLBSMN1; SMN2 | |
| SCHEMBL22816535 | 0.92 | CYP19A1 (0.45) | CYP19A1AKR1C3MAPTPOLBSMN1; SMN2 | |
| SCHEMBL29799202 | 0.90 | CYP19A1 (0.45) | CYP19A1AKR1C3MAPTPOLBSMN1; SMN2 | |
| SCHEMBL21296982 | 0.90 | CYP19A1 (0.45) | CYP19A1AKR1C3MAPTPOLBSMN1; SMN2 | |
| SCHEMBL23001982 | 0.90 | CYP19A1 (0.47) | CYP19A1AKR1C3MAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164112-A | Amide compound and preparation method, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-12-16 | — | — | CN | disclosed |