Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 17/20 | 0.54 |
| ▸ | KLK1 | P06870 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825220 | 0.87 | KLKB1 (0.56) | KLKB1KLK1MEN1KMT2ANOTUM | |
| SCHEMBL28269562 | 0.86 | KLKB1 (0.43) | KLKB1KLK1 | |
| SCHEMBL16247016 | 0.85 | KLKB1 (0.67) | KLKB1KLK1MEN1KMT2ANOTUM | |
| SCHEMBL28047222 | 0.85 | KLKB1 (0.49) | KLKB1KLK1 | |
| SCHEMBL28047179 | 0.81 | KLKB1 (0.68) | KLKB1KLK1MEN1KMT2ANOTUM | |
| SCHEMBL28047163 | 0.80 | KLKB1 (0.65) | KLKB1KLK1MEN1KMT2ANOTUM | |
| SCHEMBL28825217 | 0.80 | KLKB1 (0.54) | KLKB1KLK1 | |
| SCHEMBL28047228 | 0.80 | KLKB1 (0.59) | KLKB1KLK1 | |
| SCHEMBL28825219 | 0.79 | KLKB1 (0.65) | KLKB1KLK1MEN1KMT2ANOTUM | |
| SCHEMBL28047246 | 0.78 | KLK1 (0.54) | KLKB1KLK1MEN1KMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143201-A | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | claimed |
| CN-105143201-A | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | disclosed |