Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16046449 | 1.00 | IDH1 (0.33) | IDH1AAK1 | |
| SCHEMBL15960144 | 1.00 | IDH1 (0.33) | IDH1AAK1 | |
| SCHEMBL30484066 | 0.88 | KDM1A (0.32) | — | |
| SCHEMBL2108498 | 0.88 | — | — | |
| SCHEMBL20238255 | 0.87 | — | — | |
| SCHEMBL20238258 | 0.87 | — | — | |
| SCHEMBL20238259 | 0.87 | — | — | |
| SCHEMBL15960147 | 0.86 | IDH1 (0.30) | IDH1 | |
| SCHEMBL19191782 | 0.86 | IDH1 (0.30) | IDH1 | |
| SCHEMBL19177718 | 0.86 | IDH1 (0.30) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263929-A | 3-Pyrimidin-4-yl-oxazolidin-2-one compounds as mutant IDH inhibitors | NOVARTIS AG | 2016-01-20 | — | — | CN | disclosed |
| CN-105209460-A | 3-Pyrimidin-4-yl-oxazolidin-2-one compounds as mutant IDH inhibitors | NOVARTIS AG | 2015-12-30 | — | — | CN | disclosed |