Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047695 | 1.00 | PTPN1 (0.49) | PTPN1CD274PDCD1MAPK1MEN1 | |
| SCHEMBL28047787 | 0.87 | CD274 (0.55) | PTPN1CD274PDCD1 | |
| SCHEMBL28047785 | 0.87 | CD274 (0.55) | PTPN1CD274PDCD1 | |
| SCHEMBL28047709 | 0.86 | PTPN1 (0.49) | PTPN1CD274PDCD1MAPK1 | |
| SCHEMBL28047714 | 0.86 | PTPN1 (0.49) | PTPN1CD274PDCD1MAPK1 | |
| SCHEMBL28047834 | 0.83 | PTPN1 (0.47) | PTPN1CD274PDCD1MAPK1MEN1 | |
| SCHEMBL28047676 | 0.83 | PTPN1 (0.47) | PTPN1CD274PDCD1MAPK1 | |
| SCHEMBL28047675 | 0.83 | PTPN1 (0.47) | PTPN1CD274PDCD1MAPK1 | |
| SCHEMBL28047829 | 0.83 | PTPN1 (0.47) | PTPN1CD274PDCD1MAPK1MEN1 | |
| SCHEMBL28047704 | 0.81 | CD274 (0.57) | PTPN1CD274PDCD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | claimed |
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |