Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.43 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047778 | 1.00 | PTPN1 (0.44) | PTPN1CD274PDCD1SLC10A2CPB2 | |
| SCHEMBL28047760 | 0.84 | PTPN1 (0.45) | PTPN1CD274PDCD1 | |
| SCHEMBL28047753 | 0.84 | PTPN1 (0.45) | PTPN1CD274PDCD1 | |
| SCHEMBL28047676 | 0.83 | PTPN1 (0.47) | PTPN1CD274PDCD1MAPK1 | |
| SCHEMBL28047675 | 0.83 | PTPN1 (0.47) | PTPN1CD274PDCD1MAPK1 | |
| SCHEMBL28047785 | 0.81 | CD274 (0.55) | PTPN1CD274PDCD1 | |
| SCHEMBL28047787 | 0.81 | CD274 (0.55) | PTPN1CD274PDCD1 | |
| SCHEMBL28047828 | 0.81 | MAPK1 (0.56) | PTPN1CD274PDCD1MAPK1 | |
| SCHEMBL28047834 | 0.81 | PTPN1 (0.47) | PTPN1CD274PDCD1MAPK1 | |
| SCHEMBL28047714 | 0.80 | PTPN1 (0.49) | PTPN1CD274PDCD1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | claimed |
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |