Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.71 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.62 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.58 |
| ▸ | BTK | Q06187 | 1/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048039 | 1.00 | PIK3CD (0.71) | PIK3CDPIK3CAIRAK4BTKPIK3CB | |
| SCHEMBL28981064 | 1.00 | PIK3CD (0.71) | PIK3CDPIK3CAIRAK4BTKPIK3CB | |
| SCHEMBL31029626 | 0.94 | IRAK4 (0.65) | PIK3CDPIK3CAIRAK4BTKGPR119 | |
| SCHEMBL30902132 | 0.94 | IRAK4 (0.65) | PIK3CDPIK3CAIRAK4BTKGPR119 | |
| SCHEMBL26813748 | 0.86 | IRAK4 (0.78) | PIK3CDIRAK4 | |
| SCHEMBL21996896 | 0.86 | IRAK4 (0.78) | PIK3CDIRAK4 | |
| SCHEMBL28895304 | 0.84 | PIK3CD (0.66) | PIK3CDPIK3CAIRAK4BTKPIK3CB | |
| SCHEMBL16748148 | 0.84 | PIK3CD (0.54) | PIK3CDPIK3CAIRAK4BTKPIK3CB | |
| SCHEMBL16748147 | 0.84 | PIK3CD (0.54) | PIK3CDPIK3CAIRAK4BTKPIK3CB | |
| SCHEMBL16748284 | 0.84 | PIK3CD (0.54) | PIK3CDPIK3CAIRAK4BTKPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894451-B | Selenium-containing PI3K delta inhibitor and application thereof in diseases caused by PI3K delta overexpression and medicines | 西安爱思益生物科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-115894451-A | Selenium-containing PI3K delta inhibitor, application thereof in diseases caused by PI3K delta overexpression and medicine | 西安爱思益生物科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-105237484-B | The quinolines and its application that a kind of 6- aryl replaces | 西安交通大学 | 2018-12-07 | — | — | CN | disclosed |
| CN-105237484-A | 6-aryl substituted quinoline compounds and applications thereof | UNIV XI AN JIAOTONG | 2016-01-13 | — | — | CN | disclosed |