SCHEMBL28048

SCHEMBL28048

O=C(O)c1cnc2ccccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 1.00
CFTR P13569 1/20 0.60
KDR P35968 1/20 0.57
TOP2A P11388 2/20 0.56
TOP2B Q02880 2/20 0.56
BCAT1 P54687 1/20 0.56
RAB9A P51151 5/20 0.54
PSMD14 O00487 1/20 0.54
ALDH1A1 P00352 3/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CYP1A2 P05177 1/20 0.50
MAP4K4 O95819 1/20 0.50
CSNK1G2 P78368 1/20 0.50
CLK4 Q9HAZ1 1/20 0.50
MKNK2 Q9HBH9 1/20 0.50
MAP4K5 Q9Y4K4 1/20 0.50
NPC1 O15118 4/20 0.49
KDM4E B2RXH2 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362407 1.00 MGAM (1.00) MGAMCFTRKDRTOP2ATOP2B
SCHEMBL27611260 0.98 MGAM (0.96) MGAMCFTRKDRTOP2ATOP2B
SCHEMBL27565246 0.98 MGAM (0.96) MGAMCFTRKDRTOP2ATOP2B
Fluoride SCHEMBL27513846 0.98 MGAM (0.96) MGAMCFTRKDRTOP2ATOP2B
Water SCHEMBL28182355 0.98 MGAM (0.96) MGAMCFTRKDRTOP2ATOP2B
Hydrochloric Acid SCHEMBL9114407 0.98 MGAM (0.96) MGAMCFTRKDRTOP2ATOP2B
Ammonia Solution, Strong SCHEMBL27447121 0.98 MGAM (0.96) MGAMCFTRKDRTOP2ATOP2B
Hydrochloric Acid SCHEMBL1649216 0.98 MGAM (0.96) MGAMCFTRKDRTOP2ATOP2B
Fluoride SCHEMBL27790822 0.98 MGAM (0.96) MGAMCFTRKDRTOP2ATOP2B
Formaldehyde SCHEMBL28117649 0.96 MGAM (0.93) MGAMCFTRKDRTOP2ATOP2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3174 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
CN-116925723-B Heterocyclic organosilicon quaternary ammonium salt and active carbon blending bactericide for oil and gas field and preparation method thereof 中国石油天然气股份有限公司 2025-04-01 CN claimed
CN-117886748-A Quinoline amino acid conjugate and preparation method and application thereof 天津科技大学 2024-04-16 CN claimed
CN-117645621-B Rare earth organic red light conversion agent and preparation method and application thereof 山东济钢鲁纳新材料科技有限公司 2024-03-29 CN claimed
CN-117645621-A Rare earth organic red light conversion agent and preparation method and application thereof 山东济钢鲁纳新材料科技有限公司 2024-03-05 CN claimed
CN-117624140-A CXCR4 antagonists, methods of making and uses thereof 杭州师范大学 2024-03-01 CN claimed
CN-117050300-A Polylysine-based polymer adjuvant material, and preparation method and application thereof 中国科学院长春应用化学研究所 2023-11-14 CN claimed
CN-116925723-A Heterocyclic organosilicon quaternary ammonium salt and active carbon blending bactericide for oil and gas field and preparation method thereof 中国石油天然气股份有限公司 2023-10-24 CN claimed
CN-115466212-B 2-trifluoromethyl quinoline compound and synthetic method and application thereof 河南农业大学 2023-09-22 CN claimed
CN-116217531-A Preparation method of ethyl maltol ester and cigarette 湖北中烟工业有限责任公司 2023-06-06 CN claimed
EP-0205879-A2 Process for the preparation of herbicidal 2-(4,4-disubstituted 5-oxo-2-imidazolin-2-yl)benzoic, nicotinic and quinoline-3-carboxylic acids, esters and salts AMERICAN CYANAMID COMPANY (US) 1986-12-30 EP claimed
EP-0206747-A2 1,4-Dihydropyridine derivatives useful in the treatment of cardiovascular disorders, and a process for producing the derivatives WARNER-LAMBERT COMPANY (US) 1986-12-30 EP claimed
EP-0184027-A2 Preparation of substituted and unsubstituted 2-carbamoyl nicotinic and 3-quinolinecarboxylic acids AMERICAN CYANAMID COMPANY (US) 1986-06-11 EP claimed
US-4591415-A ADDITIVES OF PYRIDINE CARBOXYLIC ACID, PYRIDINE THIOL, GUINOLINE CARBOXYLIC ACID, QUINOLINE THIOL AND THEIR DERIVATIVES LEARONAL, INC. (US) 1986-05-27 US claimed
US-4562257-A HERBICIDES AMERICAN CYANAMID COMPANY (US) 1985-12-31 US claimed
EP-0150439-A1 An acid bath for electrodeposition of gold or gold alloys, an electroplating method and the use of said bath LeaRonal (UK) plc (GB) 1985-08-07 EP claimed
EP-0144595-A1 Preparation of 2-carbamoyl nicotinic and 3-quinoline carboxylic acids AMERICAN CYANAMID COMPANY (US) 1985-06-19 EP claimed
US-4518780-A BASE CATALYZED CYCLIZATION OF 2-CARBAMOYLNICOTINIC ACID, 3-QUIOLINECARBOXYLIC OR BENZOIL ACIDS AMERICAN CYANAMID COMPANY (US) 1985-05-21 US claimed
WO-1983004253-A1 PROCESS FOR THE PREPARATION OF 2-(5,5-DISUBSTITUTED-4-OXO-2-IMIDAZOLIN-2-YL)-NICOTINIC, QUINOLINE-3-CARBOXYLIC AND BENZOIC ACIDS AMERICAN CYANAMID COMPANY (US) 1983-12-08 WO claimed
EP-0095105-A2 Process for the preparation of 2-(5,5-disubstituted-4-oxo-2-imidazolin-2-yl)-nicotinic acids, quinoline-3-carboxylic acids, and benzoic acids AMERICAN CYANAMID COMPANY (US) 1983-11-30 EP claimed