Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15746103 | 0.94 | TDP1 (0.73) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL17032630 | 0.94 | TDP1 (0.73) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL6538839 | 0.94 | TDP1 (0.73) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL17817841 | 0.94 | TDP1 (0.73) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL14163846 | 0.89 | CA1 (0.55) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL7068776 | 0.88 | TDP1 (0.64) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL7796581 | 0.88 | TDP1 (0.64) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL14426869 | 0.88 | TDP1 (0.64) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL6474060 | 0.86 | TDP1 (0.69) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL28439234 | 0.85 | TDP1 (0.55) | TDP1MAPK1ALDH1A1CYP3A4APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566127-A | Triamine monomer and preparation method and application thereof | UNIV JILIN | 2016-05-11 | — | — | CN | disclosed |