Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048270 | 0.85 | BTK (0.76) | BTK | |
| SCHEMBL16150586 | 0.84 | BTK (0.76) | BTK | |
| SCHEMBL28048298 | 0.83 | BTK (0.68) | BTK | |
| SCHEMBL16150678 | 0.83 | BTK (1.00) | BTK | |
| SCHEMBL16150364 | 0.76 | BTK (1.00) | BTK | |
| SCHEMBL28048269 | 0.76 | BTK (0.72) | BTK | |
| SCHEMBL28825408 | 0.76 | BTK (0.70) | BTK | |
| Tert-Butyl Formate SCHEMBL28048300 | 0.76 | BTK (0.60) | BTK | |
| SCHEMBL16150857 | 0.76 | BTK (0.77) | BTK | |
| SCHEMBL16150792 | 0.75 | BTK (1.00) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105142640-A | Inhibitors of bruton's tyrosine kinase | HOFFMANN LA ROCHE | 2015-12-09 | — | — | CN | disclosed |