Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017198 | 0.91 | MRGPRX4 (0.39) | MRGPRX4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28016507 | 0.91 | MRGPRX4 (0.39) | MRGPRX4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28048621 | 0.91 | MRGPRX4 (0.41) | MRGPRX4HPGDPTGER1S1PR1S1PR5 | |
| SCHEMBL28016505 | 0.88 | MRGPRX4 (0.42) | MRGPRX4TP53PTGER1CD274 | |
| SCHEMBL28048625 | 0.84 | MRGPRX4 (0.42) | MRGPRX4HPGDTP53PTGER1 | |
| SCHEMBL28017144 | 0.83 | MRGPRX4 (0.39) | MRGPRX4CD274 | |
| SCHEMBL28016502 | 0.83 | MRGPRX4 (0.39) | MRGPRX4PTGER1 | |
| SCHEMBL28825558 | 0.81 | MRGPRX4 (0.44) | MRGPRX4PTGER1S1PR1S1PR5 | |
| SCHEMBL28016436 | 0.80 | MRGPRX4 (0.40) | MRGPRX4 | |
| SCHEMBL28016504 | 0.79 | MRGPRX4 (0.40) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263921-A | Tetrazolinone compound and application of same | SUMITOMO CHEMICAL CO | 2016-01-20 | — | — | CN | disclosed |