Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA4 | P22748 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830521 | 0.86 | CA1 (0.39) | CA1CA2CA4CA9POLB | |
| SCHEMBL25308860 | 0.86 | CA1 (0.39) | CA1CA2CA4CA9POLB | |
| SCHEMBL12439869 | 0.86 | CYP1A2 (0.43) | CA1CA2CA4CA9POLB | |
| SCHEMBL14433125 | 0.86 | CYP1A2 (0.43) | CA1CA2CA4CA9POLB | |
| SCHEMBL2015636 | 0.86 | CA1 (0.39) | CA1CA2CA4CA9POLB | |
| SCHEMBL8321488 | 0.82 | HTT (0.45) | CA1CA2CA4CA9ALDH1A1 | |
| SCHEMBL16838110 | 0.82 | HTT (0.45) | CA1CA2CA4CA9ALDH1A1 | |
| SCHEMBL25587621 | 0.82 | CA1 (0.36) | CA1CA2CA4CA9POLB | |
| SCHEMBL305616 | 0.78 | NR1H2 (0.51) | ALDH1A1RECQL | |
| SCHEMBL2157286 | 0.78 | NR1H2 (0.51) | ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377851-A | BET bromodomain inhibitors and therapeutic methods using these inhibitors | UNIV MICHIGAN REGENTS | 2016-03-02 | — | — | CN | disclosed |