Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | TFPI2 | P48307 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249823 | 0.81 | TUBB1 (0.62) | TUBB1TFPI2HDAC1HDAC6L3MBTL1 | |
| SCHEMBL2651525 | 0.77 | PIM1 (0.47) | TUBB1TFPI2KDM4EPPARDPPARA | |
| SCHEMBL28264551 | 0.76 | CYP2A6 (0.34) | TUBB1L3MBTL1POLBHTR6PLA2G4A | |
| SCHEMBL15969044 | 0.76 | CYP2A6 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5483649 | 0.74 | SRD5A2 (0.57) | HDAC1HDAC6RAB9AKDM4EALDH1A1 | |
| SCHEMBL2795863 | 0.73 | KDR (0.45) | TUBB1 | |
| SCHEMBL28048800 | 0.73 | CHEK1 (0.42) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30063197 | 0.73 | ELANE (0.47) | TUBB1TFPI2OXER1L3MBTL1TSHR | |
| SCHEMBL25857593 | 0.72 | HTR2C (0.39) | TUBB1TFPI2L3MBTL1POLBHTR6 | |
| SCHEMBL26432938 | 0.72 | CYP2A6 (0.35) | TUBB1TFPI2L3MBTL1POLBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188696-A | Gamma-diketones as WNT/beta -catenin signaling pathway activators | SAMUMED LLC | 2015-12-23 | — | — | CN | disclosed |