SCHEMBL28048795

SCHEMBL28048795

CC(C)CC(CO)n1ccnc1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 8/20 0.44
CYP19A1 P11511 8/20 0.38
KDM4E B2RXH2 1/20 0.36
CYP26A1 O43174 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14168870 0.83 CYP17A1 (0.45) CYP17A1CYP19A1
Acetic Acid SCHEMBL27980280 0.78 CYP17A1 (0.43) CYP17A1CYP19A1KDM4ECYP26A1KMT2A
SCHEMBL28774803 0.77 CYP17A1 (0.46) CYP17A1CYP19A1KDM4ECYP26A1KMT2A
SCHEMBL9459746 0.76
SCHEMBL3307573 0.76
SCHEMBL20800089 0.76 CYP17A1 (0.49) CYP17A1CYP19A1KDM4ECYP26A1KMT2A
SCHEMBL9459911 0.76
Acetic Acid SCHEMBL27980247 0.76 CYP17A1 (0.41) CYP17A1CYP19A1KDM4ECYP26A1KMT2A
SCHEMBL27980057 0.75 KMT2A (0.41) CYP17A1CYP19A1KDM4ECYP26A1KMT2A
SCHEMBL29061183 0.75 CYP19A1 (0.40) CYP17A1CYP19A1KDM4ECYP26A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105131042-A Chelate-type N-heterocyclic carbene palladium compound containing heteroaromatic group and preparation method of same UNIV HENAN TECHNOLOGY 2015-12-09 CN disclosed