Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.39 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.35 |
| ▸ | PLD2 | O14939 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28120270 | 1.00 | BIRC2 (0.49) | BIRC2HRH4CA2CHKACHRNB2 | |
| SCHEMBL27957087 | 1.00 | BIRC2 (0.49) | BIRC2HRH4CA2CHKACHRNB2 | |
| Hydrochloric Acid SCHEMBL27858891 | 0.98 | BIRC2 (0.47) | BIRC2HRH4CA2CHKACHRNB2 | |
| Hydrochloric Acid SCHEMBL28060591 | 0.98 | BIRC2 (0.47) | BIRC2HRH4CA2CHKACHRNB2 | |
| Hydrochloric Acid SCHEMBL27858885 | 0.98 | BIRC2 (0.47) | BIRC2HRH4CA2CHKACHRNB2 | |
| SCHEMBL190023 | 0.84 | BIRC2 (0.47) | BIRC2HRH4CA2CHKACHRNB2 | |
| SCHEMBL1181669 | 0.84 | BIRC2 (0.47) | BIRC2HRH4CA2CHKACHRNB2 | |
| SCHEMBL190024 | 0.84 | BIRC2 (0.47) | BIRC2HRH4CA2CHKACHRNB2 | |
| SCHEMBL2418463 | 0.84 | BIRC2 (0.47) | BIRC2HRH4CA2CHKACHRNB2 | |
| SCHEMBL2422071 | 0.84 | BIRC2 (0.47) | BIRC2HRH4CA2CHKACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458985-B | 6-heteroaryloxy-and 6-aryloxy-quinoline-2-carboxamides and their use | 艾伯维公司 | 2019-05-03 | — | — | CN | claimed |
| CN-106458985-A | 6-heteroaryloxy-and 6-aryloxy-quinoline-2-carboxamides and their use | 艾伯维公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106458985-B | 6-heteroaryloxy-and 6-aryloxy-quinoline-2-carboxamides and their use | 艾伯维公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-106458985-A | 6-heteroaryloxy-and 6-aryloxy-quinoline-2-carboxamides and their use | 艾伯维公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105377851-A | BET bromodomain inhibitors and therapeutic methods using these inhibitors | UNIV MICHIGAN REGENTS | 2016-03-02 | — | — | CN | disclosed |