Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.53 |
| ▸ | PPARG | P37231 | 6/20 | 0.53 |
| ▸ | PPARD | Q03181 | 6/20 | 0.53 |
| ▸ | PPARA | Q07869 | 6/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL28832818 | 1.00 | USP2 (0.75) | USP2MEN1KMT2AKDM4EDUSP3 | |
| Batilol SCHEMBL28050096 | 1.00 | USP2 (0.75) | USP2MEN1KMT2AKDM4EDUSP3 | |
| Octanoic Acid SCHEMBL28725968 | 1.00 | USP2 (0.75) | USP2MEN1KMT2AKDM4EDUSP3 | |
| Stearic Acid SCHEMBL28804039 | 1.00 | USP2 (0.75) | USP2MEN1KMT2AKDM4EDUSP3 | |
| Stearic Acid SCHEMBL28436825 | 1.00 | USP2 (0.75) | USP2MEN1KMT2AKDM4EDUSP3 | |
| Palmitic Acid SCHEMBL28215317 | 1.00 | USP2 (0.75) | USP2MEN1KMT2AKDM4EDUSP3 | |
| Dodecanoate SCHEMBL394038 | 1.00 | USP2 (0.75) | USP2MEN1KMT2AKDM4EDUSP3 | |
| Dodecanoate SCHEMBL28995146 | 1.00 | USP2 (0.75) | USP2MEN1KMT2AKDM4EDUSP3 | |
| Palmitic Acid SCHEMBL28358922 | 0.97 | USP2 (0.71) | USP2MEN1KMT2AKDM4EDUSP3 | |
| Decanoic Acid SCHEMBL28285361 | 0.97 | USP2 (0.71) | USP2MEN1KMT2AKDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105343165-A | Polyhexamethylene guanidine propionate lotion, gel and suppository for department of gynecology | WEI GUOGANG | 2016-02-24 | — | — | CN | disclosed |
| CN-104434778-A | Preparation method of polyhexamethylene guanidine gel and suppository | WEI GUOGANG | 2015-03-25 | — | — | CN | disclosed |