Benzene

Benzene

SCHEMBL28049392

O=C(O)Br.c1ccccc1

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
TSHR P16473 5/20 0.36
ALDH1A1 P00352 4/20 0.36
RECQL P46063 2/20 0.36
THRB P10828 1/20 0.36
CES2 O00748 3/20 0.35
CES1 P23141 3/20 0.35
DAO P14920 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
ALOX15 P16050 1/20 0.35
CYP2C19 P33261 2/20 0.33
TP53 P04637 2/20 0.33
PTPN1 P18031 2/20 0.33
GSK3B P49841 1/20 0.33
ACHE P22303 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29245197 0.88
SCHEMBL233908 0.88
SCHEMBL28016195 0.82
Hydrochloric Acid SCHEMBL7128655 0.82
SCHEMBL27729110 0.82
Ammonia Solution, Strong SCHEMBL31146935 0.82
Benzene SCHEMBL27441606 0.80 FFAR3 (0.50) CA1CA2CA9TSHRALDH1A1
Ethane SCHEMBL10381112 0.78
Ethylene SCHEMBL28887996 0.78 CA1 (0.40) CA1CA2CA9TSHRALDH1A1
Ethylene SCHEMBL28525646 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105384703-A Thiazolidinedione chemical compound preparation method UNIV HENAN 2016-03-09 CN disclosed