Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | EP300 | Q09472 | 1/20 | 0.55 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.51 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291943 | 0.92 | GAA (0.84) | GAAPOLBHTTPAX8KMT2A | |
| SCHEMBL1599021 | 0.88 | GAA (0.78) | GAAPOLBHTTPAX8KMT2A | |
| SCHEMBL11270312 | 0.85 | GAA (0.74) | GAAPOLBHTTPAX8KMT2A | |
| SCHEMBL14680244 | 0.84 | GAA (0.72) | GAAPOLBHTTPAX8KMT2A | |
| SCHEMBL1597896 | 0.82 | GAA (0.70) | GAAPOLBHTTPAX8KMT2A | |
| SCHEMBL9637318 | 0.81 | GAA (0.68) | GAAPOLBHTTPAX8KMT2A | |
| SCHEMBL19419936 | 0.81 | GAA (0.68) | GAAPOLBHTTPAX8KMT2A | |
| SCHEMBL8291152 | 0.80 | GAA (1.00) | GAAPOLBHTTPAX8KMT2A | |
| SCHEMBL3105212 | 0.79 | GAA (0.65) | GAAPOLBHTTPAX8KMT2A | |
| SCHEMBL3105199 | 0.79 | GAA (0.65) | GAAPOLBHTTPAX8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218457-A | A kind of preparation method of 3,5,5 '-three replacement-2-thiohydantoin | UNIV SHANDONG | 2016-01-06 | — | — | CN | claimed |
| CN-105218457-A | A kind of preparation method of 3,5,5 '-three replacement-2-thiohydantoin | UNIV SHANDONG | 2016-01-06 | — | — | CN | disclosed |