Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | ILK | Q13418 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28049942 | 0.91 | ENPP1 (0.55) | ENPP1KDRFGFR1FLT1PDE4A | |
| SCHEMBL1346309 | 0.89 | PDE4A (0.44) | ENPP1KDRFGFR1FLT1PDE4A | |
| SCHEMBL8147583 | 0.87 | ENPP1 (0.55) | ENPP1KDRFGFR1FLT1PDE4A | |
| SCHEMBL30640012 | 0.87 | ENPP1 (0.55) | ENPP1KDRFGFR1FLT1PDE4A | |
| SCHEMBL5044674 | 0.86 | PDE4A (0.42) | ENPP1KDRFGFR1FLT1PDE4A | |
| SCHEMBL4512570 | 0.86 | KDR (0.57) | ENPP1KDRFGFR1FLT1PDE4A | |
| SCHEMBL3424568 | 0.86 | PDE4A (0.44) | ENPP1KDRFGFR1FLT1PDE4A | |
| SCHEMBL4514446 | 0.85 | HRH3 (0.48) | FGFR1SMN1; SMN2KDM4ESRCLSS | |
| Hydrochloric Acid SCHEMBL5566426 | 0.85 | KDR (0.56) | ENPP1KDRFGFR1FLT1PDE4A | |
| SCHEMBL4501873 | 0.84 | MAPT (0.47) | FGFR1KDM4ESRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294578-A | Quinazoline derivative having targeted antitumor activity | GUANGDONG WHOLEWIN TECHNOLOGY CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-105294578-A | Quinazoline derivative having targeted antitumor activity | GUANGDONG WHOLEWIN TECHNOLOGY CO LTD | 2016-02-03 | — | — | CN | disclosed |