Phosphine

Phosphine

SCHEMBL28051578

O=[PH]1Oc2ccccc2-c2ccccc21.P

nearest known ligand 0.34

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.34
PKM P14618 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
ALOX15 P16050 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30781 0.98 HSP90AA1 (0.35) HSP90AA1PKMTSHRKDM4EMAPK1
SCHEMBL29395467 0.98 HSP90AA1 (0.35) HSP90AA1PKMTSHRKDM4EMAPK1
SCHEMBL29363087 0.98 HSP90AA1 (0.35) HSP90AA1PKMTSHRKDM4EMAPK1
SCHEMBL28437933 0.96 HSP90AA1 (0.34) HSP90AA1PKMTSHRKDM4EMAPK1
Bromide SCHEMBL28619414 0.96 HSP90AA1 (0.34) HSP90AA1PKMTSHRKDM4EMAPK1
SCHEMBL6444080 0.96 HSP90AA1 (0.34) HSP90AA1PKMTSHRKDM4EMAPK1
SCHEMBL30598814 0.96 HSP90AA1 (0.34) HSP90AA1PKMTSHRKDM4EMAPK1
SCHEMBL31183036 0.96 HSP90AA1 (0.34) HSP90AA1PKMTSHRKDM4EMAPK1
SCHEMBL28045782 0.90 HSP90AA1 (0.32) HSP90AA1
Carbon Tetrachloride SCHEMBL28073880 0.90 HSP90AA1 (0.32) HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105203691-B The analysis determining method of extraordinary phosphonium flame retardant in copolyester hot melt adhesive nethike embrane 上海天洋热熔粘接材料股份有限公司 2017-06-13 CN claimed
CN-105203691-A Analysis determination method for special phosphate-containing fire retardant in copolyester hot-melt adhesive netted film SHANGHAI TIANYANG HOT MELT ADHESIVES CO LTD 2015-12-30 CN claimed
CN-114031641-A Phosphorus-nitrogen flame retardant compound, preparation method thereof and method for preparing flame-retardant epoxy resin by using phosphorus-nitrogen flame retardant compound 哈尔滨工程大学 2022-02-11 CN disclosed
CN-105203691-B The analysis determining method of extraordinary phosphonium flame retardant in copolyester hot melt adhesive nethike embrane 上海天洋热熔粘接材料股份有限公司 2017-06-13 CN disclosed
CN-105203691-A Analysis determination method for special phosphate-containing fire retardant in copolyester hot-melt adhesive netted film SHANGHAI TIANYANG HOT MELT ADHESIVES CO LTD 2015-12-30 CN disclosed