Morpholine

Morpholine

SCHEMBL28052158

C1COCCN1.CCC(=O)C1CNCCO1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 5/20 0.40
REN P00797 10/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
CYP2C9 P11712 1/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23230712 0.93 SSTR4 (0.44) SSTR4RENSLC6A2SLC6A4
SCHEMBL295081 0.93 SSTR4 (0.44) SSTR4RENSLC6A2SLC6A4
Diethylamine SCHEMBL29018336 0.85 SSTR4 (0.43) SSTR4RENSLC6A2SLC6A4
SCHEMBL17559282 0.79 SSTR4 (0.42) SSTR4RENSLC6A2SLC6A4
SCHEMBL7310959 0.77 SSTR4 (0.42) SSTR4REN
SCHEMBL2817040 0.76 SSTR4 (0.41) SSTR4RENMEN1KMT2AKDM4E
SCHEMBL294388 0.76 SSTR4 (0.46) SSTR4REN
SCHEMBL9204612 0.76 SSTR4 (0.46) SSTR4RENSLC6A2SLC6A4
SCHEMBL2720664 0.75 SSTR4 (0.40) SSTR4REN
SCHEMBL2688364 0.75 SSTR4 (0.41) SSTR4RENSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110498776-B Synthesis method for preparing acryloylmorpholine by using acrylamide as raw material 浙江鑫甬生物化工股份有限公司 2023-06-27 CN disclosed
CN-105315232-B A kind of preparation method of acryloyl morpholine 天津久日新材料股份有限公司 2018-01-05 CN disclosed
CN-105315232-A Method for preparing acryloyl morpholine TIANJIN JIURI NEW MATERIALS CO LTD 2016-02-10 CN disclosed