Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 17/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884187 | 0.94 | PIK3CD (0.70) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL28052415 | 0.92 | PIK3CG (0.67) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL21029040 | 0.86 | PIK3CD (0.70) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884188 | 0.86 | PIK3CD (0.72) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884196 | 0.86 | PIK3CD (0.72) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884154 | 0.84 | PIK3CD (0.75) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9883990 | 0.83 | PIK3CG (0.73) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL954290 | 0.82 | PIK3CD (0.83) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL29903215 | 0.82 | PIK3CD (0.83) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9883993 | 0.82 | PIK3CD (0.68) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431437-A | PI3K protein kinase inhibitors, in particular inhibitors and/or gamma inhibitors | RHIZEN PHARMACEUTICALS SA | 2016-03-23 | — | — | CN | claimed |
| CN-105431437-A | PI3K protein kinase inhibitors, in particular inhibitors and/or gamma inhibitors | RHIZEN PHARMACEUTICALS SA | 2016-03-23 | — | — | CN | disclosed |