Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.70 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.70 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.70 |
| ▸ | ABL1 | P00519 | 1/20 | 0.70 |
| ▸ | SRC | P12931 | 1/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.70 |
| ▸ | PRKDC | P78527 | 1/20 | 0.70 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917210 | 0.94 | PIK3CD (0.79) | PIK3CDPIK3CGPIK3CBPIK3CAABL1 | |
| SCHEMBL1952680 | 0.82 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CBPIK3CAABL1 | |
| SCHEMBL29381345 | 0.82 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CBPIK3CAABL1 | |
| SCHEMBL31326456 | 0.82 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CBPIK3CAABL1 | |
| SCHEMBL7913535 | 0.81 | PIK3CD (0.80) | PIK3CDPIK3CGPIK3CBPIK3CAABL1 | |
| SCHEMBL12108103 | 0.80 | PIK3CD (0.79) | PIK3CDPIK3CGPIK3CBPIK3CAABL1 | |
| SCHEMBL12108155 | 0.80 | PIK3CD (0.79) | PIK3CDPIK3CGPIK3CBPIK3CAABL1 | |
| SCHEMBL16004754 | 0.80 | PIK3CD (0.88) | PIK3CDPIK3CGPIK3CBPIK3CAABL1 | |
| SCHEMBL7908392 | 0.80 | PIK3CD (0.88) | PIK3CDPIK3CGPIK3CBPIK3CAABL1 | |
| SCHEMBL12109895 | 0.79 | PIK3CD (0.78) | PIK3CDPIK3CGPIK3CBPIK3CAABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431437-A | PI3K protein kinase inhibitors, in particular inhibitors and/or gamma inhibitors | RHIZEN PHARMACEUTICALS SA | 2016-03-23 | — | — | CN | claimed |
| CN-105431437-A | PI3K protein kinase inhibitors, in particular inhibitors and/or gamma inhibitors | RHIZEN PHARMACEUTICALS SA | 2016-03-23 | — | — | CN | disclosed |