Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385289 | 0.95 | NPC1 (0.61) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL27792112 | 0.93 | NPC1 (0.59) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL5092287 | 0.85 | HDAC3 (0.61) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL1262591 | 0.83 | HDAC3 (0.64) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL27530055 | 0.82 | HDAC3 (0.67) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL27853144 | 0.82 | HDAC3 (0.67) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL5145338 | 0.82 | HDAC3 (0.67) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL28973854 | 0.82 | HDAC3 (0.67) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL28968193 | 0.82 | HDAC3 (0.67) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL28401199 | 0.81 | NPC1 (0.61) | NPC1RAB9AHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330569-A | Preparation method of (R)-2-(N-tertbutyloxycarbonylamino)biphenylpropanol | TONGJING OPTOELECTRONICS TECHNOLOGY CO LTD | 2016-02-17 | — | — | CN | disclosed |