(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL28053570

C(=Cc1ccccc1)c1ccccc1.COC

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.68
NFE2L2 Q16236 3/20 0.60
MAOB P27338 2/20 0.58
TUBB1 Q9H4B7 2/20 0.58
TUBB4A P04350 1/20 0.58
TUBB P07437 1/20 0.58
TUBA3C P0DPH7 1/20 0.58
TUBA1B P68363 1/20 0.58
TUBA4A P68366 1/20 0.58
TUBB4B P68371 1/20 0.58
TUBB3 Q13509 1/20 0.58
TUBB2A Q13885 1/20 0.58
TUBB8 Q3ZCM7 1/20 0.58
TUBA3E Q6PEY2 1/20 0.58
TUBA1A Q71U36 1/20 0.58
TUBA1C Q9BQE3 1/20 0.58
TUBB6 Q9BUF5 1/20 0.58
TUBB2B Q9BVA1 1/20 0.58
CYP1A1 P04798 1/20 0.58
CYP1A2 P05177 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL21847984 0.87 MAOB (0.73) TRPA1NFE2L2MAOBCHATCYP19A1
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.87 MAOB (0.73) TRPA1NFE2L2MAOBCHATCYP19A1
(Z)-1,2-Diphenylethene SCHEMBL442 0.87 MAOB (0.73) TRPA1NFE2L2MAOBCHATCYP19A1
(Z)-1,2-Diphenylethene SCHEMBL443 0.87 MAOB (0.73) TRPA1NFE2L2MAOBCHATCYP19A1
(Z)-1,2-Diphenylethene SCHEMBL9134296 0.87 MAOB (0.73) TRPA1NFE2L2MAOBCHATCYP19A1
(Z)-1,2-Diphenylethene SCHEMBL9488270 0.87 MAOB (0.73) TRPA1NFE2L2MAOBCHATCYP19A1
(Z)-1,2-Diphenylethene SCHEMBL9488275 0.87 MAOB (0.73) TRPA1NFE2L2MAOBCHATCYP19A1
(Z)-1,2-Diphenylethene SCHEMBL347707 0.87 MAOB (0.73) TRPA1NFE2L2MAOBCHATCYP19A1
(Z)-1,2-Diphenylethene SCHEMBL22712863 0.87 MAOB (0.73) TRPA1NFE2L2MAOBCHATCYP19A1
(Z)-1,2-Diphenylethene SCHEMBL23852642 0.83 MAOB (0.69) TRPA1NFE2L2MAOBCHATCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103083288-B By using pterostilbene and alleviate oxidative stress and improving the method for working memory US AGRICULTURE (US) 2016-04-13 CN disclosed