Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 2/20 | 0.31 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4098477 | 0.86 | DYRK1A (0.39) | DYRK1ANTRK1 | |
| Hydrazine SCHEMBL28204704 | 0.85 | DYRK1A (0.44) | DYRK1AROCK2ROCK1CDK2 | |
| SCHEMBL29506231 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL28492555 | 0.83 | DYRK1A (0.45) | DYRK1ACDK2 | |
| Phosphine SCHEMBL27502321 | 0.83 | DYRK1A (0.45) | DYRK1ACDK2 | |
| Bromide SCHEMBL26621962 | 0.83 | DYRK1A (0.45) | DYRK1ACDK2 | |
| SCHEMBL4222803 | 0.83 | DYRK1A (0.45) | DYRK1ACDK2 | |
| Iodide SCHEMBL1296857 | 0.83 | DYRK1A (0.45) | DYRK1ACDK2 | |
| Hydrochloric Acid SCHEMBL18284548 | 0.83 | DYRK1A (0.45) | DYRK1ACDK2 | |
| Formamide SCHEMBL28262825 | 0.82 | DYRK1A (0.39) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102295642-B | 2-Aryimidazole is [1,2-a] pyridine-3-acetamide, Preparation Method And The Use also | Institute of Toxicology and Drugs, Chinese Academy of Military Medical Sciences (CN) | 2016-04-06 | — | — | CN | disclosed |