Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.86 |
| ▸ | ABL1 | P00519 | 8/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | CLK1 | P49759 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | CSF1R | P07333 | 1/20 | 0.62 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856181 | 0.93 | KIT (1.00) | KITABL1CSF1RFGFR1KDR | |
| SCHEMBL4103102 | 0.93 | KIT (1.00) | KITABL1CSF1RFGFR1KDR | |
| SCHEMBL16250591 | 0.92 | KIT (0.85) | KITABL1CSF1RFGFR1KDR | |
| SCHEMBL16755299 | 0.91 | KIT (0.87) | KITABL1CSF1RFGFR1KDR | |
| SCHEMBL4095171 | 0.91 | KIT (0.84) | KITABL1CSF1RFGFR1KDR | |
| SCHEMBL16250590 | 0.90 | KIT (0.82) | KITABL1CSF1RFGFR1KDR | |
| SCHEMBL30080773 | 0.89 | KIT (0.93) | KITABL1CSF1RFGFR1KDR | |
| SCHEMBL17936186 | 0.89 | KIT (0.93) | KITABL1CSF1RFGFR1KDR | |
| SCHEMBL28054441 | 0.88 | ABL1 (0.69) | KITABL1HTT | |
| SCHEMBL30309801 | 0.87 | KIT (0.69) | KITHTTCLK1MAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103467385-B | Bicyclic heteroaryl compounds | ARIAD GENE THERAPEUTICS INC. (US) | 2016-03-09 | — | — | CN | disclosed |