SCHEMBL28054640

SCHEMBL28054640

c1ccc2cc(C(c3ccc4ccccc4c3)c3ccc4cc5ccccc5cc4c3)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.56
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ATM Q13315 1/20 0.47
CYP3A4 P08684 3/20 0.46
HIF1A Q16665 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALOX15 P16050 1/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
HBB P68871 1/20 0.46
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
KCNH2 Q12809 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP1A2 P05177 2/20 0.43
AOC3 Q16853 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2837489 0.95 UGT2B7 (0.60) UGT2B7MEN1KMT2AATMCYP3A4
SCHEMBL5011133 0.91 UGT2B7 (0.47) UGT2B7CYP3A4HIF1AALDH1A1HSD17B10
SCHEMBL1056867 0.88 UGT2B7 (0.54) UGT2B7MEN1KMT2AATMCYP3A4
SCHEMBL2491495 0.83 UGT2B7 (0.65) UGT2B7MEN1KMT2AATMCYP3A4
SCHEMBL6885490 0.83 UGT2B7 (0.65) UGT2B7MEN1KMT2AATMCYP3A4
Anthracene SCHEMBL22288151 0.83 UGT2B7 (0.65) UGT2B7MEN1KMT2AATMCYP3A4
SCHEMBL10296815 0.82 CYP1A2 (0.58) UGT2B7MEN1KMT2AATMCYP3A4
SCHEMBL31409235 0.82 CYP3A4 (0.58) UGT2B7MEN1KMT2AATMCYP3A4
SCHEMBL18481572 0.79 CYP2A6 (0.54) UGT2B7CYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL1538476 0.78 UGT2B7 (0.48) UGT2B7MEN1KMT2AATMCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776335-A Amine derivant of pyrene and preparation method thereof, application and device 武汉尚赛光电科技有限公司 2019-05-21 CN disclosed
CN-105503622-A Benzo[c]phenanthrene derivative with electron donor-acceptor structure and application thereof and electroluminescent device WUHAN SHANGSAI OPTOELECTRONICS TECH CO LTD 2016-04-20 CN disclosed