Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898376 | 0.76 | MCL1 (0.56) | MCL1GAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8063164 | 0.74 | MCL1 (0.48) | MCL1GAAMAPK1RXFP1KMT2A | |
| SCHEMBL2265092 | 0.73 | MCL1 (0.54) | MCL1GAAMAPK1RXFP1KMT2A | |
| SCHEMBL238792 | 0.71 | MCL1 (0.30) | MCL1 | |
| SCHEMBL1899348 | 0.71 | MCL1 (0.50) | MCL1GAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1904226 | 0.71 | MCL1 (0.50) | MCL1GAAMAPK1RXFP1KMT2A | |
| SCHEMBL26123879 | 0.70 | MCL1 (0.57) | MCL1GAAMAPK1RXFP1KMT2A | |
| SCHEMBL11862304 | 0.70 | MCL1 (0.48) | MCL1GAAMAPK1RXFP1KMT2A | |
| SCHEMBL27550296 | 0.69 | — | — | |
| SCHEMBL28099171 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105395539-A | Application of sodium teriflunomide to preparation of medicine for treating autoimmune diseases | CINKATE PHARMACEUTICAL CHEMICAL INTERMEDIATES (SHANGHAI) CORP | 2016-03-16 | — | — | CN | disclosed |