Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.73 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 6/20 | 0.51 |
| ▸ | GAK | O14976 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 9/20 | 0.51 |
| ▸ | LCK | P06239 | 3/20 | 0.50 |
| ▸ | JAK3 | P52333 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 3/20 | 0.49 |
| ▸ | KIF5B | P33176 | 2/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.49 |
| ▸ | STK10 | O94804 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.49 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28225926 | 0.85 | PDE10A (0.60) | PDE10AACHEBACE1EGFRGAK | |
| SCHEMBL17780927 | 0.84 | PDE10A (0.78) | PDE10AACHEBACE1EGFRGAK | |
| SCHEMBL5864878 | 0.81 | PDE10A (0.65) | PDE10AEGFRGAKSRCKDR | |
| SCHEMBL18158149 | 0.80 | PDE10A (0.79) | PDE10AEGFRSRCKDRPDGFRA | |
| SCHEMBL17781038 | 0.80 | PDE10A (0.71) | PDE10AEGFRKDRPDGFRA | |
| SCHEMBL2476964 | 0.78 | RET (0.55) | PDE10AEGFRGAKSRCKDR | |
| SCHEMBL30264706 | 0.78 | PDE10A (0.52) | PDE10AEGFRGAKKDRJAK3 | |
| SCHEMBL27740786 | 0.78 | PDE10A (0.52) | PDE10AEGFRGAKSRCKDR | |
| SCHEMBL23075143 | 0.76 | KDR (0.62) | EGFRGAKSRCKDRLCK | |
| SCHEMBL1985538 | 0.76 | LCK (0.66) | ACHEBACE1EGFRGAKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408312-A | Quinoline derivatives | ONO PHARMACEUTICAL CO | 2016-03-16 | — | — | CN | disclosed |