Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 3/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336794 | 0.92 | SETD7 (0.52) | SETD7USP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL26132028 | 0.91 | HPGD (0.48) | SETD7USP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL26132034 | 0.91 | HPGD (0.48) | SETD7USP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL17560370 | 0.89 | SETD7 (0.50) | SETD7USP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL26666330 | 0.89 | SETD7 (0.50) | SETD7USP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL17560369 | 0.89 | SETD7 (0.50) | SETD7USP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL28060463 | 0.89 | SETD7 (0.50) | SETD7USP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL17560383 | 0.87 | SETD7 (0.49) | SETD7USP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL4681348 | 0.87 | SETD7 (0.49) | SETD7USP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL21806131 | 0.87 | SETD7 (0.49) | SETD7USP2SMN1; SMN2NR1H2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294655-A | CDK small-molecule inhibitor compounds and application therefore | GUANGDONG HEC PHARMACEUTICAL | 2016-02-03 | — | — | CN | disclosed |